Hydrogen bonds at the binding interface of the Rbfox*•pre-miR20b* complex during simulations.

The average donor-acceptor distances and angles are calculated over the entire simulation ensemble for the trajectory frames in which the individual H-bonds are observed and the interactions are further characterized by their occupancy in the individual simulation trajectories. The trajectories are numbered as in Table 1.

针对观测到单个氢键（H-bond）的轨迹帧，基于完整模拟系综计算得到平均供体-受体距离与角度；随后通过各模拟轨迹中相互作用的占据率对这类氢键相互作用进行进一步表征。所有模拟轨迹的编号均与表1一致。