Structure-activity relationships and lead optimization summary of VU0077625 scaffold.

IC50 values were derived from 11-point CRCs on AeKir1 in Tl+ flux experiments performed in triplicate on two separate days. Structure-activity relationships and lead optimization summary of VU0077625 scaffold.半最大抑制浓度（IC50）数值来源于针对AeKir1的铊离子流（Tl+ flux）实验，该实验于两个独立实验日内各开展三次重复，共得到11条浓度-反应曲线（CRC）。本数据集涵盖VU0077625骨架的构效关系与先导化合物优化总结。