GINS4 suppresses ferroptosis by antagonizing p53 acetylation with Snail
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GINS4 suppresses ferroptosis by antagonizing p53 acetylation with Snail
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2023-03-21
相关数据集
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3
Numerous mechanisms to support cells under conditions of transient nutrient starvation have been described. The tumor suppressor protein p53 can contribute to the adaptation of cells to metabolic stre
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Expression profile of HCT116 p53+/+ and P53-/- cells treated with Leptomycin B. Homo sapiens
HCT116 wild type cells express p53. The isogenic HCT116 p53KO cells have the p53 gene knocked out. Cells were treated for 16 hours. Dosages for leptomycin B treatment was 2 nM and 20 nM. Overall desig
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Glutamine inhibition combined with CD47 blockade enhances radiotherapy-induced ferroptosis in head and neck squamous cell carcinoma [ChIP-Seq IRF-1]. Glutamine inhibition combined with CD47 blockade enhances radiotherapy-induced ferroptosis in head and neck squamous cell carcinoma [ChIP-Seq IRF-1]
To investigate the glutamine inhibition combined with CD47 blockade regulation of ferroptosis in HNSCC. We then performed gene expression profiling analysis using data obtained from RNA-seq of 3 diffe
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Ribo-Seq experiments in HCT116 WT and TP53-/- cells upon neocarzinostatin treatment. Ribo-Seq experiments in HCT116 WT and TP53-/- cells upon neocarzinostatin treatment
The transcription factor p53 exerts its tumor suppressive effects through transcriptional activation of numerous target genes controlling cell cycle arrest, apoptosis, cellular senescence and DNA repa
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Effect of MDM2 overexpression on response to etoposide treatment
We aimed to study the effect of non-mutational p53 inactivation on the response of hematopoietic progenitor cells to genotoxic treatment. In order to study this in vitro, we generated HSPC lines by en
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