Rabbit hemorrhagic disease virus strain:Turretfield 2009 Genome sequencing and assembly

Variant viruses were selected by serially passaging a highly virulent rabbit haemorrhagic disease virus field isolate in laboratory rabbits, which were passively immunised with a neutralising monoclonal antibody.

研究人员通过在经中和性单克隆抗体被动免疫的实验家兔体内，对一株高毒力兔出血症病毒（rabbit haemorrhagic disease virus）野外分离株进行连续传代，进而筛选获得变异病毒毒株。