Hazard ratios of breast cancer when data from the randomized WHI study are analyzed as a fictive observational study.

Model 1 is a regression model with 3 year follow-up (scenario 1); model 2 is the same model assuming that 10% starts using hormones every year in the non-user group (scenario 2); in model 3 (scenario 3) it is assumed that the incidence rates in the fictive study were identical to that observed for all 16 608 women of the WHI trial. In parenthesis we also give HR when assuming that 5% start using hormones every year in the non-user groups.
Hazard ratios of breast cancer when data from the randomized WHI study are analyzed as a fictive observational study.

模型1为随访时长3年的回归模型（场景1）；模型2为同一回归模型，假设非激素使用者组每年有10%的人群启动激素使用（场景2）；模型3（场景3）则假定该模拟研究中的发病率与妇女健康倡议（Women's Health Initiative, WHI）试验全部16608名女性的观测发病率一致。此外，我们还在括号中给出了假定非激素使用者组每年有5%的人群启动激素使用时的风险比（Hazard Ratio, HR）。
本数据集为将随机对照妇女健康倡议研究的数据作为模拟观察性研究进行分析后得到的乳腺癌风险比。