Large B-cell lymphoma imprints dysfunctional immune phenotype that persists years after treatment

Comprehensive study of the immune fingerprint of lymphoma and immunotherapy on DLBCL survivors MDSCs and activated CD4 T cells were sorted and their RNA was sequenced

本研究针对淋巴瘤的免疫特征以及免疫治疗对弥漫大B细胞淋巴瘤（Diffuse Large B-Cell Lymphoma, DLBCL）幸存者的影响开展系统性探究，实验过程中对髓系来源抑制性细胞（Myeloid-Derived Suppressor Cells, MDSCs）与活化CD4阳性T细胞进行分选，并对其RNA进行测序。