Expression data from lung resident mesenchymal stem cells from idiopathic pulmonary fibrosis patients and control subjects. Expression data from lung resident mesenchymal stem cells from idiopathic pulmonary fibrosis patients and control subjects

Lung resident mesenchymal stem cells exert a pivotal role in tissue repair. Idiopathic pulmonary fibrosis is characterized by an aberrant tissue repair. We performed a transcriptomic analysis to characterize lung resident mesenchymal stem cells from idiopathic pulmonary fibrosis patients Overall design: Lung resident mesenchymal stem cells were isolated from idiopathic pulmonary fibrosis patients and control subjects. RNA was isolated from cultured cells and transcriptomic analysis were performed by using the GeneChip® Gene 1.0 ST Array System (Affymetrix)

肺驻留间充质干细胞（lung resident mesenchymal stem cells）在组织修复中发挥关键作用。特发性肺纤维化（idiopathic pulmonary fibrosis）以异常组织修复为典型病理特征。本研究通过转录组分析，对特发性肺纤维化患者的肺驻留间充质干细胞进行特征鉴定。
实验设计概述：
本研究从特发性肺纤维化患者与健康对照受试者中分离肺驻留间充质干细胞；从培养的细胞中提取RNA，并使用GeneChip® Gene 1.0 ST Array系统（Affymetrix）完成转录组分析。