首页/数据集/MOG-encoding DNA vaccines ameliorate EAE and display neuroprotective effects in treated mice summary

MOG-encoding DNA vaccines ameliorate EAE and display neuroprotective effects in treated mice summary

ChEBI2011-07-08 更新2026-07-21 收录

自身免疫性脑脊髓炎

DNA疫苗神经保护

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-30482 数据链接链接失效反馈

官方服务：

资源简介：

MOG-encoding DNA vaccines ameliorate EAE and display neuroprotective effects in treated mice summary

应用场景：

创建时间：

2011-07-08

自身免疫性脑脊髓炎

Toll样受体

Innate receptors, including Toll like receptors (TLRs), are implicated in pathogenesis of CNS inflammatory diseases such as multiple sclerosis (MS) and its animal model experimental autoimmune encepha

NIAID Data Ecosystem90

Preferential use of public T cell receptors during autoimmune encephalomyelitis determined by high resolution saturating sequencing

T细胞受体库

自身免疫性脑脊髓炎

How the TCR repertoire, in concert with risk-associated MHC, imposes susceptibility for autoimmune diseases is incompletely resolved. Due largely to recombinatorial biases, a small fraction of TCR ? o

NIAID Data Ecosystem40

Myelin-reactive B cells exacerbate the severity of CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner

自身免疫性脑脊髓炎

神经细胞分子互作

mRNA sequencing of Tph cells (CD4+PD1+CXCR5-) and B cells (CD19+) from IgH(MOG) mice on the NOD background and WT control. Cells were sorted with ARIA-II high speed sorter from the CNS of mice reachin

NIAID Data Ecosystem10

Genetic deletion of Autotaxin from CD11b + cells decreases the severity of experimental autoimmune encephalomyelitis

神经免疫学

自身免疫性脑脊髓炎

Autotaxin (ATX) is a secreted lysophospholipase D catalyzing the extracellular production of lysophosphatidic acid (LPA), a growth factor-like signaling lysophospholipid. ATX and LPA signaling have be

NIAID Data Ecosystem80

Transplantation of hESC-derived NPs significantly attenuates the clinical severity of EAE.

干细胞治疗

自身免疫性脑脊髓炎

Transplantation of hESC-derived NPs significantly attenuates the clinical severity of EAE.

NIAID Data Ecosystem20