Genomic mining of Vibrio parahaemolyticus highlights prevalence of antimicrobial resistance genes and new genetic markers associated with AHPND and tdh trh positive genotypes

Acute Hepatopancreatic Necrosis Disease , previously referred to as Early Mortality Syndrome, is an emerging bacterial disease in shrimp. It has inflicted substantial economic losses in the shrimp industry, especially in Asian countries such as Thailand, Vietnam, and Malaysia, but also South America and the United States. This AHPND is caused by specific strains of the Gram negative bacterium Vibrio parahaemolyticus carrying a conjugative plasmid of approximately 69 kbp in size, housing the pirABvp genes.

急性肝胰腺坏死病（Acute Hepatopancreatic Necrosis Disease, AHPND）曾被称为早期死亡综合征（Early Mortality Syndrome, EMS），是一种新兴的虾类细菌性病害。该病害给虾养殖业造成了巨额经济损失，尤其重创泰国、越南、马来西亚等亚洲国家的虾产业，同时也对南美地区及美国的虾养殖业带来严重影响。AHPND由携带特定接合性质粒的副溶血性弧菌（Vibrio parahaemolyticus）菌株引发，这类质粒大小约为69千碱基对（kbp），其上携带有pirABvp基因。