Multimodal Neuroimaging Dataset of Meige Syndrome

This dataset is a part of a study investigating the differences in brain regions among patients with Meige syndrome (MS), providing clues for understanding the neural mechanisms of Meige syndrome. All participants were recruited from the Department of Neurosurgery at China-Japan Friendship Hospital. The inclusion criteria for MS patients were a diagnosis of primary Meige syndrome by an experienced senior neurosurgeon based on standard clinical criteria, no other craniocerebral lesions or psychiatric diseases, and right-handedness.This dataset consists of multimodal neuroimaging data from 31 right-handed MS patients (23 females; 31-74 years old, mean = 58.32, SD = 9.60). The brain images were acquired using a 3.0 Tesla scanner (GE MRI 750) at the China-Japan Friendship Hospital. The multimodal imaging protocol included a set of MRI sequences of the high-resolution T1-weighted structural MRI (sMRI), resting-state functional MRI (fMRI), diffusion tensor imaging (DTI) and arterial spin labeling (ASL) MRI.We are releasing these data for both research and education training in human brain sciences. Specifically, to protect personal information, we applied the face masking toolkit to achieve privacy anonymization by blurring facial information while all the participants agreed to share their anonymized data to the public. To monitor the quality of all structural and functional images for each participant, we also employed MRI_QC toolkit for generating reports on the data quality, which are included in the sharing. All data structures conform to the specification of BIDS data structure.

本数据集为一项探讨梅杰综合征（Meige syndrome, MS）患者脑区差异的研究组成部分，可为解析梅杰综合征的神经机制提供线索。所有研究对象均招募自中日友好医院神经外科。梅杰综合征患者的纳入标准为：由经验丰富的资深神经外科医师依据标准临床诊疗规范确诊为原发性梅杰综合征，无其他颅脑病变或精神疾病，且为右利手。本数据集包含31名右利手梅杰综合征患者的多模态神经影像数据，其中女性23名，年龄跨度为31~74岁，平均年龄58.32岁，标准差（Standard Deviation, SD）为9.60。脑部影像于中日友好医院采用3.0特斯拉扫描仪（GE MRI 750）采集。该多模态成像方案涵盖高分辨率T1加权结构磁共振成像（structural MRI, sMRI）、静息态功能磁共振成像（functional MRI, fMRI）、弥散张量成像（diffusion tensor imaging, DTI）及动脉自旋标记磁共振成像（arterial spin labeling, ASL）序列。本数据集面向人脑科学领域的研究与教育教学场景公开共享。为保护受试者个人信息，我们采用面部掩膜工具包对其面部信息进行模糊处理以实现隐私匿名化，所有受试者均同意将其匿名化数据公开共享。为监控每位受试者的结构与功能影像质量，我们同时使用MRI_QC工具包生成数据质量报告，并随数据集一并共享。所有数据结构均符合脑成像数据结构（Brain Imaging Data Structure, BIDS）规范。