Genetic variants in cytokine and metastatic potential genes included in the current study.

ap-value of the Hardy-Weinberg equilibrium testing for genotypes evaluated in the entire study population. *marks genotype distributions which did not meet HWE, later removed from analyses. Abbreviations used for cytokines and metastasis-associated gene variants: IFN-γ – interferon-γ; IL: various interleukins; TNF – tumor-necrosis factors; TGF-β1 – transforming growth factor-beta-1; IGF-2R – insulin-like growth factor 2 receptor; MMP-1 – matrix metalloproteinase 1.针对全部研究人群中评估的基因型所开展的哈迪-温伯格平衡（Hardy-Weinberg equilibrium, HWE）检验的P值。 *号标记了不符合哈迪-温伯格平衡的基因型分布，此类基因型后续被从分析中剔除。 本研究中用于细胞因子与转移相关基因变异的缩写说明如下：IFN-γ——干扰素-γ（interferon-γ）；IL——各类白细胞介素（interleukins）；TNF——肿瘤坏死因子（tumor-necrosis factors）；TGF-β1——转化生长因子-β1（transforming growth factor-beta-1）；IGF-2R——胰岛素样生长因子2受体（insulin-like growth factor 2 receptor）；MMP-1——基质金属蛋白酶1（matrix metalloproteinase 1）。