Predictions of EnzymeExplorer for UniRef90 clusters with no InterPro annotations

This dataset contains the results of predictions by the software EnzymeExplorer on UniRef90 clusters that are longer than 230 amino acid residues and do not have any annotation in InterPro, making them a protein dark matter. 

Enzyme explorer predicts whether a protein belongs to the family of terpene synthases (TPS). The dataset is a csv file with the following columns:

ID - The UniProt id of the predicted sequence

sequence - The amino acid sequence of the protein

isTPS - A confidence score if this protein is a terpene synthase. The lowest scores that have been experimentally observed to be functional terpene synthases are about 0.35

precursor substr - A confidence score if this protein is a isoprenyl diphosphate synthase, that is the enzyme responsible for synthesis of TPS substrates. Enzymes that are isoprenyl diphosphate synthases have usually low isTPS scores

Substrates (8 columns) - Confidence scores for predictions of substrates accepted by this enzyme

本数据集包含EnzymeExplorer软件针对UniRef90聚类簇的预测结果。此类聚类簇的氨基酸序列长度超过230个残基，且在InterPro数据库中无任何注释信息，属于蛋白质暗物质（protein dark matter）。

EnzymeExplorer可预测蛋白质是否隶属于萜烯合酶（terpene synthases, TPS）家族。本数据集为CSV格式文件，包含如下列项：
- ID：待预测序列的UniProt标识符
- sequence：蛋白质的氨基酸序列
- isTPS：该蛋白质属于萜烯合酶的置信度得分。经实验验证具备功能的萜烯合酶，其最低观测到的置信度得分约为0.35
- precursor substr：该蛋白质属于异戊二烯二磷酸合酶（isoprenyl diphosphate synthase，即负责合成TPS底物的酶）的置信度得分。异戊二烯二磷酸合酶通常具有较低的isTPS得分
- Substrates（共8列）：该酶所接受底物的预测置信度得分