Characteristics of SAPALDIA follow-up participants at baseline (1991; upper part), follow-up (2002; middle part), and between the two examinations (lower part).

AAT: Alpha1-antitrypsin; BMI: Body mass index; ETS: regularly exposed to environmental tobacco smoke; FEF25-75%: mid expiratory flow; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; hs-CRP: high-sensitivty C-reactive protein; IQR: Interquartile range; SD: Standard deviation.aPearson's χ2 test for testing equal proportions, analysis of variance (ANOVA) for testing equal means of normally distributed data (AAT levels and spirometric measurements), and Kruskal-Wallis test for testing equal distributions in not normally distributed data (age and BMI values) between the three genotype classes.bObese subjects were defined as having a BMI≥30kg/m2.AAT：α₁-抗胰蛋白酶(Alpha1-antitrypsin)；BMI：体质量指数(Body mass index)；ETS：定期暴露于环境烟草烟雾(regularly exposed to environmental tobacco smoke)；FEF25-75%：25%~75%用力呼气流速(mid expiratory flow)；FEV1：1秒用力呼气容积(forced expiratory volume in 1 second)；FVC：用力肺活量(forced vital capacity)；hs-CRP：高敏C反应蛋白(high-sensitivity C-reactive protein)；IQR：四分位间距(Interquartile range)；SD：标准差(Standard deviation)。a. 采用Pearson χ²检验比较三类基因型组间的构成比差异；对于符合正态分布的数据（AAT水平及肺量测定参数），采用方差分析（ANOVA）比较组间均数差异；对于不符合正态分布的数据（年龄与BMI值），采用Kruskal-Wallis检验比较组间分布差异。b. 肥胖受试者定义为体质量指数（BMI）≥30kg/m²。