Comparison of DMN sub-network dwell time between Alzheimer’s and age-, gender-, and education-matched cognitive normal subjects.

The median, IQR, and p-values from the Wilcoxon two-sided rank sum test are reported for the age, education, STMS, CDR-SOB, and dwell time in strong DMN sub-network modular configurations for AD subjects and age-, gender-, and education-matched CN subjects (the gender proportions and the p-value of the chi-squared test between groups is reported as well). DMN dwell time is defined as the proportion of time (reported as a percentage) that a subject spends in a particular modular configuration (strong DMN sub-network configurations in this case) during the TF-fMRI scanning session.
AD-Alzheimer’s disease, STMS-short test of mental status, CDR-SOB-clinical dementia rating scale sum of boxes, aDMN-anterior default mode network, DT-dwell time, pDMN-posterior default mode network, vDMN-ventral default mode network, dDMN-dorsal default mode network, CN-cognitively normal, IQR-interquartile range, TF-fMRI-task-free functional magnetic resonance imaging.

本研究针对阿尔茨海默病（Alzheimer’s disease）受试者，以及年龄、性别与教育程度匹配的认知正常（cognitively normal）对照组受试者，报告了两组在年龄、简易精神状态测试（short test of mental status）、临床痴呆评定量表总分（clinical dementia rating scale sum of boxes），以及强默认模式网络（default mode network, DMN）子网络模块化配置下的停留时间（dwell time）的中位数、四分位距（interquartile range），以及Wilcoxon双侧秩和检验（Wilcoxon two-sided rank sum test）的p值；同时还报告了两组的性别构成比例，以及组间卡方检验的p值。
默认模式网络停留时间定义为：受试者在无任务态功能磁共振成像（task-free functional magnetic resonance imaging, TF-fMRI）扫描过程中，处于特定模块化配置（本研究中为强默认模式网络子网络配置）的时间占比，以百分比形式报告。

本研究涉及的缩写及对应译法如下：AD：阿尔茨海默病（Alzheimer’s disease）；STMS：简易精神状态测试（short test of mental status）；CDR-SOB：临床痴呆评定量表总分（clinical dementia rating scale sum of boxes）；aDMN：前部默认模式网络（anterior default mode network）；DT：停留时间（dwell time）；pDMN：后部默认模式网络（posterior default mode network）；vDMN：腹侧默认模式网络（ventral default mode network）；dDMN：背侧默认模式网络（dorsal default mode network）；CN：认知正常（cognitively normal）；IQR：四分位距（interquartile range）；TF-fMRI：无任务态功能磁共振成像（task-free functional magnetic resonance imaging）。