Additional file 2 of Identification of asthma-related genes using asthmatic blood eQTLs of Korean patients

Additional file 2: Table S2. eQTL results showing allelic effects in the opposite direction, between the asthmatic and normal eQTL data; Table S3. Results for 148 loci significantly associated with asthma in the GWAS analysis of the UK Biobank for colocalization analysis; Table S4. Results for 11 loci significantly associated with asthma in the GWAS analysis of the Japanese cohort for colocalization analysis; Table S5. Significant colocalization genes of three eQTL datasets; Table S6. Shared eGenes of significant colocalization between GTEx and Japanese; Table S7. Significant results of SMR analysis; Table S8. Significant results of TWAS analysis; Table S9. Asthma susceptibility genes and interacting asthma drugs.

附加文件2：表S2：表达数量性状位点（expression quantitative trait locus, eQTL）分析结果，展示哮喘组与正常组eQTL数据间方向相反的等位基因效应；表S3：英国生物库（UK Biobank）全基因组关联分析（genome-wide association study, GWAS）中148个与哮喘显著相关的位点的共定位分析结果；表S4：日本队列全基因组关联分析中11个与哮喘显著相关的位点的共定位分析结果；表S5：三个eQTL数据集的显著共定位基因；表S6：基因型-组织表达（Genotype-Tissue Expression, GTEx）与日本队列显著共定位分析结果中共有的表达基因（expression gene, eGene）；表S7：基于汇总数据的孟德尔随机化（summary Mendelian randomization, SMR）分析显著结果；表S8：转录组全基因组关联分析（transcriptome-wide association study, TWAS）显著结果；表S9：哮喘易感基因及其相互作用的哮喘治疗药物