Simulated ancient metagenomic dataset enriched for microbial pathogens

This is a simulated ancient metagenomic dataset enriched for microbial pathogens. The dataset was used for replication of the benchmarking the anciemt microbiome profiling workflow aMeta against Heuristic Operations for Pathogen Screening (HOPS), see link under references. The dataset was simulated using gargammel software, see link under references. Both ancient and modern reads were simulated, sequencing errors and Illumina adapters were added. The simulated datase was built by Nikolay Oskolkov, Lund University, Sweden, within the NBIS SciLifeLab long-term support project, PI Anders Götherström, Centre for Palaeogenetics, Stockholm, Sweden.本数据集为富集了微生物病原体的模拟古代宏基因组数据集。本数据集用于重复验证古代微生物组分析流程aMeta针对病原体筛选启发式操作（Heuristic Operations for Pathogen Screening，HOPS）的基准测试性能，相关参考文献链接见文末。本数据集通过gargammel软件模拟生成，相关参考文献链接见文末。模拟过程中同时生成了古代与现代测序读段（reads），并添加了测序错误与Illumina接头序列。本模拟数据集由瑞典隆德大学的Nikolay Oskolkov在NBIS SciLifeLab长期支持项目中构建，项目首席研究员（PI）为瑞典斯德哥尔摩古遗传学中心的Anders Götherström。