The crystal structures at 2.2 angstroms resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations

The crystal structures at 2.2 angstroms resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations

针对结合人类免疫缺陷病毒1型蛋白酶（human immunodeficiency virus type 1 protease）的羟乙烯基抑制剂（hydroxyethylene-based inhibitors）所解析得到的2.2埃分辨率晶体结构表明，该类抑制剂在晶体中存在两种截然不同的结合取向。