Cocaine infusions earned before and during the dose-response challenge

This data set represents the number of cocaine infusions each subject earned for the last two days preceding (2a), and for the two consecutive sessions during (2b), the dose-response challenge for mice of each genotype. TRPC5 +/+ = wild-type; TRPC5 -/- = knock-down; "-2" = second to last day leading up to dose-response challenge; "-1" = last day leading up to dose-response challenge; S(0.05) = session with dose 0.05 mg/kg/infusion; S(0.1) = session with dose 0.1 mg/kg/infusion; S(0.75) = session with dose 0.75 mg/kg/infusion; S(2.0) = session with does 2.0 mg/kg/infusion; S1 = first daily session with respective dose; S2 = second daily session with respective dose

本数据集记录了各基因型小鼠在剂量-反应给药挑战前两日（2a）以及挑战期间连续两次实验环节（2b）中，每只实验对象获得的可卡因输注次数。其中TRPC5 +/+ 为野生型（wild-type），TRPC5 -/- 为基因敲低（knock-down）；符号“-2”代表剂量-反应给药挑战前的倒数第二日，“-1”代表剂量-反应给药挑战前的最后一日；S(0.05) 指给药剂量为0.05 mg/kg/输注的实验环节，S(0.1)、S(0.75)、S(2.0)分别对应给药剂量为0.1 mg/kg/输注、0.75 mg/kg/输注、2.0 mg/kg/输注的实验环节；S1为对应剂量下每日的首个实验环节，S2为对应剂量下每日的第二个实验环节。