Human Airway Smooth Muscle Transcriptome Changes in Response to Asthma Medications
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Human Airway Smooth Muscle Transcriptome Changes in Response to Asthma Medications
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创建时间：
2014-01-01
相关数据集
Human Airway Smooth Muscle Transcriptome Changes in Response to Asthma Medications
Rationale: Asthma is a chronic inflammatory airway disease. The most common medications used for its treatment are Ã2-agonists and glucocorticosteroids, and one of the primary tissues that these drug
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An inhaled dose of budesonide induces genes involved in transcription and signaling in human airways
Inhaled corticosteroids (ICS) control airway inflammation in mild to moderate asthma by reducing inflammatory gene expression. However, incomplete understanding of the molecular mechanisms underpinnin
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Airway smooth muscle reponse to dexamathasone at 4 and 24 hours
Glucocorticoids, which activate glucocorticoid receptor signaling and thus modulate gene expression, are widely used to treat asthma. Glucocorticoids exert their therapeutic effects in part through mo
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P4M3 Small airway - mRNA [Processed]
This dataset was generated in an in vitro systems toxicology study where Human organotypic small airway cultures were exposed at the air-liquid interface to cigarette smoke and aerosols of different f
DataCite Commons2020-07-23 更新80
Anti-asthmatic effect of nafamostat is associated with modulated expression of pro-inflammatory genes, reduced eosinophil infiltration and attenuated airway hyperreactivity. Anti-asthmatic effect of nafamostat is associated with modulated expression of pro-inflammatory genes, reduced eosinophil infiltration and attenuated airway hyperreactivity
Asthma is typically characterized by an imbalance between the expression of proteases and of inhibitors capable of neutralizing such enzymes. Hence, an attractive option for intervening with asthma co
NIAID Data Ecosystem60
