The mouse ENCODE (ENCyclopedia Of DNA Elements) Project.. Mouse ENCODE project

The Mouse ENCODE project is a two-year effort, supported with ARRA funds, to discover and use relationships between mouse and human regulatory sequences to advance the ENCODE Project in its effort to map all functional elements in the human genome. The Mouse ENCODE project seeks to study cell types, tissues, and experimental conditions that cannot be addressed in human, to yield a broader compendium of functional genomic elements. By harnessing comparative genomics analyses and techniques, the Mouse ENCODE project aims to uncover principles and solve problems that are proving difficult by studying the human genome alone.

小鼠ENCODE（Mouse ENCODE）项目是一项为期两年的研究计划，由美国复苏与再投资法案（ARRA）资助，旨在揭示并利用小鼠与人类调控序列之间的关联，以推进ENCODE（Encyclopedia of DNA Elements）项目对人类基因组全部功能元件的图谱绘制工作。该项目旨在研究无法在人类样本中开展的细胞类型、组织与实验条件，从而构建更为全面的功能基因组元件汇编目录。通过运用比较基因组学分析方法与技术手段，该项目旨在挖掘仅通过单独研究人类基因组所难以发现的规律，并解决相关难题。