Additional file 5 of Too much or too little opioids to patients receiving opioid agonist therapy in Norway (2013–2017): a prospective cohort study

Additional file 5. Logistic regression of factors associated with being dispensed an opioid analgesic. OAT: opioid agonist therapy; cOR: crude odds ratio; aOR: adjusted odds ratio; CI: confidence interval. * The type of OAT opioid that was dispensed on the last dispensation per year. ** We defined the OAT opioid dose ratio as a mean daily dose of dispensed OAT opioids divided by mean recommended dose of OAT opioids per day (18 mg buprenorphine or 18/4.5 mg buprenorphine/naloxone, 90 mg methadone or 45 mg levomethadone). A ratio of one indicated that patients were dispensed a mean daily dose of OAT opioids equal to the mean recommended dose per day. The table displays the association between being dispensed an opioid analgesic and age groups, gender, palliative care, chronic pain, the number of dispensations of OAT opioids, the type of dispensed OAT opioid, and the OAT opioid dose ratio among patients who were dispensed an OAT opioid at least monthly per year in the period 2013–2017.附加文件5：阿片类镇痛药物配发相关影响因素的Logistic回归分析。OAT：阿片受体激动剂治疗（opioid agonist therapy）；cOR：粗比值比（crude odds ratio）；aOR：校正比值比（adjusted odds ratio）；CI：置信区间（confidence interval）。* 每年末次配发的阿片受体激动剂治疗所用阿片类药物类型。** 本研究将阿片受体激动剂治疗的阿片类药物剂量比值定义为：配发的阿片受体激动剂类药物日均剂量除以日均推荐剂量（18mg丁丙诺啡，或18/4.5mg丁丙诺啡/纳洛酮，90mg美沙酮或45mg左美沙酮）。当该比值为1时，代表患者获得的阿片受体激动剂类药物日均配发剂量等于日均推荐剂量。本表格展示了2013-2017年间，每年至少每月获得1次阿片受体激动剂类药物配发的患者中，阿片类镇痛药物配发情况与年龄分组、性别、姑息治疗、慢性疼痛、阿片受体激动剂类药物配发次数、配发的阿片受体激动剂类药物类型以及阿片受体激动剂类药物剂量比值之间的关联。