Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells

To identify YAP and TFCP2 co-regulated genes, RNA-seq was also performed in Bel-7402 cells before and after knocking down YAP or TFCP2. From the RNA-seq data, 2165 genes were found that were possibly co-regulated by YAP and TFCP2. Examination of YAP and TFCP2 down-regulated genes in Bel-7402 cells.

为鉴定YAP与TFCP2的共同调控基因，本研究在Bel-7402细胞中分别敲低YAP或TFCP2的前后均开展了RNA测序（RNA-seq）实验。从该RNA-seq数据中，共筛选得到2165个可能受YAP与TFCP2共同调控的基因。本研究同时对Bel-7402细胞中YAP及TFCP2敲低后下调的基因进行了检测分析。