Look-up table for assessment of iron content in Magtrace® samples based on Sentimag®

Following the administration of a magnetic tracer (Magtrace®, Endomagnetics Ltd. UK), the Sentimag® device (Endomagnetics Ltd. UK) is employed as a handheld magnetic tool to identify the initial draining lymph node(s) originating from a primary tumour, commonly known as the sentinel lymph node (SLN). The evaluation is primarily qualitative and does not yield information regarding the quantity of iron tracer present in the SLN. A look-up table (LUT) dataset has been created exclusively for the Sentimag® handheld probe (Endomagnetics ltd. UK). This LUT serves the purpose of quantifying the accumulation of Magtrace magnetic tracer within SLN through the utilisation of magnetic readout counts.Data collection involved six repeated magnetic measurements on 15 Magtrace® samples, each with a total volume of 35µL. The iron content of these samples ranged from of 0 to 504 µg, encompassing the following amounts: 0, 1.12µg, 5.04µg, 10.08µg, 28µg, 50.4µg, 100.8µg, 120µg, 140µg, 182µg, 210µg, 252µg, 280µg, 420µg, and 504µg. For data analysis, a first-order polynomial-fit method was employed to interpolate the magnetic counts and iron content by a custom-made software (Matlab version R2021b, Mathworks).The LUT is available as an Excel file, comprising four columns that encompass the outcomes of the interpolation process for various settings (1, 2, and 3).These columns consist of the iron content expressed in µg (column A) and and the relating counts for setting 1, 2 and 3 in the respective columns B, C and D. Moreover, the file includes a visual representation in the form of a figure, depicting the plotted data derived from the measured values as well as the fitted data resulting from the analysis.

在施用磁性示踪剂（Magtrace®，英国Endomagnetics有限公司生产）后，使用Sentimag®设备（英国Endomagnetics有限公司生产）这一手持式磁性工具，以识别源自原发性肿瘤的前哨引流淋巴结，即通常所称的前哨淋巴结（SLN）。该评估主要为定性性质，无法提供前哨淋巴结内铁磁性示踪剂的含量信息。本研究专为Sentimag®手持式探头（英国Endomagnetics有限公司）构建了查找表（LUT）数据集。该查找表可通过磁读出计数，实现对前哨淋巴结内Magtrace®磁性示踪剂聚集量的定量分析。数据采集阶段，对15份体积均为35µL的Magtrace®样本进行了6次重复磁性测量。这些样本的铁含量范围为0至504 µg，具体包含以下梯度：0、1.12µg、5.04µg、10.08µg、28µg、50.4µg、100.8µg、120µg、140µg、182µg、210µg、252µg、280µg、420µg及504µg。数据分析环节，采用一阶多项式拟合方法，通过定制化软件（Matlab R2021b版，美国MathWorks公司）对磁计数与铁含量进行插值处理。本查找表以Excel文件形式提供，共包含四列数据，涵盖了三种配置（1、2、3）下的插值计算结果：A列为以µg为单位的铁含量，B、C、D列依次对应配置1、2、3下的相关磁计数。此外，该文件还附带一幅可视化图表，展示了实测数据与经分析得到的拟合数据的绘制结果。