Otriginal Western blots

The data were generated to investigate the role of EDEM1 in glucose-stimultaed insulin secretion in pancreatic beta cells. We found that insulin biosynthesis and secretion are enhanced in INS-1E cells and in human islets. The ER stress of EDEM1 expressing cells is also investigated.

本数据集的生成旨在探究EDEM1在胰腺β细胞葡萄糖刺激胰岛素分泌过程中的作用。研究发现，在INS-1E细胞与人类胰岛中，胰岛素的生物合成与分泌均得到增强。本研究同时对表达EDEM1的细胞的内质网应激（ER stress）情况进行了探究。