RNA-seq with metabolic labelling of human lymphoblast cell line K562 treated with a panel of 83 different epigenetically active compounds and untreated controls. RNA-seq with metabolic labelling of human lymphoblast cell line K562 treated with a panel of 83 different epigenetically active compounds and untreated controls

This experiment has utilized metabolic labeling coupled with RNA-sequencing to identify directly responding genes after perturbing cellular enzymes affecting epigenetic modifications.

本实验采用代谢标记结合RNA测序（RNA-sequencing）技术，在对影响表观遗传修饰的细胞酶进行扰动后，鉴定直接应答基因。