Nodular melanoma - Female, 79 - Tissue image [9190729564902421]

This is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 79Clinical description: 2,6 x 1,8 x 0,2 cm light-brown lesion of skin of dorsum.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: NEVI AND MELANOMASDiagnosis: Nodular melanomaResult of the histopathological examination: Melanoma: nodular subtype, Clark IV, Breslow 2 mm, mitotic index 4 mitoses per 1 mm2, regression is present. TILS: BRISK. Complete excision. Melan A+, HMB45+, CK5/6-, Ki-67 10%.Sample:Material: FFPECollecting method: Excision of lesionsTopography: SKINOrgan: SKINTissue: Skin of backType of staining: positive/IHCStaining: Not applicableAntibody: Melan ATechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）采集并保存于ZMDL-GUMED的皮肤组织样本的组织病理学图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪以20倍放大倍率采集，并存储为DICOM格式。
患者、样本及诊断的详细信息如下：
患者信息：年龄79岁；临床特征：背部皮肤可见大小为2.6×1.8×0.2cm的浅褐色皮损；性别：女性。
诊断分类：采用ICD-O_3.2分类体系，分类编码为NEVI AND MELANOMAS（痣与黑色素瘤）；最终诊断：结节性黑色素瘤。
组织病理学检查结果：黑色素瘤为结节亚型，Clark分级IV级，Breslow厚度为2mm，核分裂象指数为每1mm²有4个核分裂象，存在退行性变；肿瘤浸润淋巴细胞（Tumor Infiltrating Lymphocytes，TILS）为BRISK型；已完成完整切除。免疫组化检测结果：Melan A阳性、HMB45阳性、CK5/6阴性、Ki-67增殖指数为10%。
样本详情：
材质：福尔马林固定石蜡包埋（FFPE）样本；
采集方式：皮损切除术；
病变部位：背部皮肤；
所属器官：皮肤；
染色类型：免疫组化（IHC）阳性；
常规染色：无适用需求；
所用抗体：Melan A；
成像设备与参数：Pannoramic 250 3DHistech玻片扫描仪，镜头倍率20倍；
数据来源机构：格但斯克医科大学。