CCLE Aneuploidy Data

Table of aneuploidy information from Cohen-Sharir et al., Selective vulnerability of aneuploid human cancer cells to inhibition of the spindle assembly checkpoint. https://doi.org/10.1101/2020.06.18.159038.Arm-level CNA calls and aneuploidy scores calculated based on CCLE ABSOLUTE copy number profiles (Ghandi et al., Nature, 2019).For a detailed description of the methods see Cohen-Sharir et al. https://doi.org/10.1101/2020.06.18.159038.本数据集为Cohen-Sharir等人发表于《非整倍体人类癌细胞对纺锤体组装检验点（spindle assembly checkpoint）抑制的选择性脆弱性（Selective vulnerability of aneuploid human cancer cells to inhibition of the spindle assembly checkpoint）》的非整倍体（aneuploidy）信息表格，对应DOI：10.1101/2020.06.18.159038。数据集包含基于癌症细胞系百科（Cancer Cell Line Encyclopedia, CCLE）的ABSOLUTE绝对拷贝数谱计算得到的染色体臂水平拷贝数变异（Copy Number Aberration, CNA）调用结果与非整倍体评分，相关计算方法源自Ghandi等人2019年发表于《自然》（Nature）的研究。若需了解实验方法的详细描述，请参阅Cohen-Sharir等人的研究，DOI：10.1101/2020.06.18.159038。