Cryo-EM structure of Drs2p-Cdc50p in the E1 state with PI4P and Mg2+ bound
收藏Protein Data Bank Japan2024-11-20 更新2026-03-28 收录
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Cryo-EM structure of Drs2p-Cdc50p in the E1 state with PI4P and Mg2+ bound Descriptor: (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Timcenko, M, Dieudonne, T, Montigny, C, Boesen, T, Lyons, J.A, Lenoir, G, Nissen, P. Deposit date: 2021-05-09 Release date: 2021-06-09 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of substrate-independent phosphorylation in a P4-ATPase lipid flippase J.Mol.Biol., 2021
结合磷脂酰肌醇4-磷酸（PI4P）与Mg²+的E1构象Drs2p-Cdc50p复合物冷冻电镜结构
描述符：(2R)-1-{[(R)-羟基{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-四羟基-4-(膦酰氧基)环己基]氧基}磷酰]氧基}-3-(十八烷酰氧基)丙-2-基(5Z,8Z,11Z,14Z)-二十碳-5,8,11,14-四烯酸酯、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖……
作者：Timcenko, M、Dieudonne, T、Montigny, C、Boesen, T、Lyons, J.A、Lenoir, G、Nissen, P
提交日期：2021-05-09
发布日期：2021-06-09
最后修改日期：2024-11-20
实验方法：电子显微镜（3 Å）
引用文献：P4-ATPase脂质翻转酶中不依赖底物的磷酸化结构基础，J.Mol.Biol., 2021
创建时间：
2021-05-09
