Annulation of Benzamides with [60]Fullerene through Palladium(II)-Catalyzed C−H Bond Activation

Palladium-catalyzed heteroannulation of N-substituted benzamides with [60]fullerene, which proceeds through direct sp2 C−H bond activation to form 7-membered ring pallada-intermediate with C60, led to formation of [60]fulleroisoquinolinones in moderate to good yields (8−64% based on recovered C60). A plausible reaction pathway is proposed.钯催化N-取代苯甲酰胺与[60]富勒烯（[60]Fullerene）的杂环化反应，该反应通过直接sp² C−H键活化，与C₆₀形成七元环钯中间体，最终以中等至良好的产率（基于回收的C₆₀计算，产率为8%~64%）生成[60]富勒烯并异喹啉酮类化合物，并提出了合理的反应路径。