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The MIDOG++ dataset represents an extension of the data set used in the MIDOG 2021 and 2022 challenges. We provide region of interest images from 503 histological specimens of seven different tumor types with variable morphology: breast carcinoma, lung carcinoma, lymphosarcoma, neuroendocrine tumor, cutaneous mast cell tumor, cutaneous melanoma, and (sub)cutaneous soft tissue sarcoma. The human and canine samples were processed and stained at different human and veterinary pathology laboratories with standard H&E dye and digitized with different digital whole slide image scanners. We provide labels for 11,937 mitotic figures that have been differentiated against 14,351 imposter cells in a blinded consensus by two pathologists and a final decision by a third pathologist for disagreed labels.MIDOG++数据集是MIDOG 2021与MIDOG 2022挑战赛所用数据集的扩展版本。本数据集提供了7种形态学特征各异的肿瘤类型的503份组织学标本的感兴趣区域（region of interest, ROI）图像，涵盖的肿瘤类型包括乳腺癌、肺癌、淋巴肉瘤、神经内分泌肿瘤、皮肤肥大细胞瘤、皮肤黑色素瘤以及（皮下）软组织肉瘤。本次研究中的人类与犬类样本均由多家人类病理学与兽医学病理学实验室采用标准苏木精-伊红（Hematoxylin-Eosin, H&E）染料进行处理与染色，并通过多款数字化全玻片图像扫描仪完成数字化扫描。数据集附带11937个有丝分裂象（mitotic figures）的标注标签，该标注由两名病理学家通过盲法共识审核完成，从14351个疑似有丝分裂的干扰细胞中甄别出上述有丝分裂象；对于标注存在分歧的样本，将由第三名病理学家作出最终判定。