Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2. Goenka et al

Complete dataset associated with manuscript "Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2. Goenka et al".
All samples arranged by their nomenclature in the paper (infants I1-4; mothers M1-3; fathers F1-4; PCR-confirmed adult controls C1-10; pre-pandemic serum samples PP1-PP9).
The folder "ELISA serum and saliva" contains original OD600nm data, and relative units for LIPS (Luciferase ImmunoPrecipitation System) assays as indicated, and corresponds to Fig. 1A-D & Fig. S1 in manuscript.
The folder "Neutralisation" contains data describing percentage of SARS-CoV-2 infected cells relative to control wells containing virus only (no sera), and corresponds to Fig. 1E-F & Fig. S2.
The folder "ELISpot" contains SFU/million PBMC data (after background unstimulated subtraction) and corresponds to Fig. 2A and S3A-B.
The folder "Intracellular Cytokine Staining FCS files" contains original FACS acquisition data (with compensation controls) in folders per each experiment and corresponds to Fig. 2B-F and Fig. S3C-F.

本完整数据集关联于论文《幼儿对新型冠状病毒（SARS-CoV-2）表现出强劲的功能性抗体应答与受限的γ干扰素（IFN-γ）产生》（Goenka 等）。
所有样本均按照论文中的命名规则进行分组：幼儿样本I1~I4、母亲样本M1~M3、父亲样本F1~F4、经聚合酶链式反应（PCR）确认的成年对照组样本C1~C10，以及大流行前血清样本PP1~PP9。
名为"ELISA血清与唾液检测"的文件夹包含原始OD600nm数据，以及标注说明的荧光素酶免疫沉淀系统（Luciferase ImmunoPrecipitation System, LIPS）检测相对单位数据，对应论文中的图1A-D与补充图S1。
名为"中和实验"的文件夹包含以仅含病毒（无血清）对照孔为基准的SARS-CoV-2感染细胞百分比数据，对应论文中的图1E-F与补充图S2。
名为"酶联免疫斑点（ELISpot）"的文件夹包含每百万外周血单个核细胞（PBMC）的斑点形成单位（SFU）数据（已扣除未刺激背景值），对应论文中的图2A与补充图S3A-B。
名为"细胞内细胞因子染色FCS文件"的文件夹包含各实验分组下的原始流式细胞术（FACS）采集数据（含补偿对照），对应论文中的图2B-F与补充图S3C-F。