In vitro exposure of rat hepatocytes to a variety of toxicants, assayed by Affymetrix microarray

DrugMatrix is a comprehensive rat toxicogenomics database and analysis tool developed to facilitate the integration of toxicogenomics into hazard assessment. Using the whole genome and a diverse set of compounds allows a comprehensive view of most pharmacological and toxicological questions and is applicable to other situations such as disease and development. Complete Drug Matrix dataset for primary rat hepatocytes. Cells were exposed to toxicants in culture medium and harvested after 0.67 or 1 day.

DrugMatrix 是一款综合性的大鼠毒理基因组学（toxicogenomics）数据库与分析工具，旨在推动毒理基因组学技术整合至危险度评估工作流程中。该工具依托全基因组覆盖范围与多样化的化合物库，可对绝大多数药理学与毒理学相关问题提供全面且深入的解析，其应用场景亦可拓展至疾病研究、发育生物学等多个领域。本数据集为原代大鼠肝细胞的完整DrugMatrix数据集，实验过程中将细胞置于培养基中暴露于各类毒物，并分别于0.67天及1天后收集样本。