Genome sequencing of Clostridium botulinum Groups I-IV and Clostridium butyricum. Clostridium botulinum

The increasing availability of C. botulinum genome sequences is now allowing the genomic diversity of C. botulinum Groups I, II, III, IV and botulinum toxin-containing Clostridia such as Clostridium butyricum to be characterised. This information will impact on microbiological food safety through improved surveillance and tracing/tracking during outbreaks, including the risk presented, and new insights into their biology, food chain transmission, and evolution.

肉毒梭菌（Clostridium botulinum）基因组序列的可获取性日益提升，当前已可对I、II、III、IV群肉毒梭菌，以及产肉毒毒素的丁酸梭菌（Clostridium butyricum）等梭菌属细菌的基因组多样性开展解析。该类研究成果将通过强化暴发疫情期间的监测与溯源追踪工作（涵盖相关风险的研判），以及深化对这类细菌生物学特性、食物链传播途径与演化历程的认知，为微生物食品安全领域带来积极影响。