Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer

RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors select the best treatment for patients and predict their response to treatment.
PURPOSE: This randomized phase II/III trial is studying how well tumor tissue testing works in selecting treatment for patients with metastatic or locally advanced colorectal cancer.

研究背景：在实验室中对癌症患者的肿瘤组织样本开展研究，可帮助医生进一步明晰DNA所发生的异常改变，并筛选出与癌症相关的生物标志物；同时还有助于医生为患者遴选最佳治疗方案，预测其对治疗的应答反应。
试验目的：本随机化II/III期临床试验旨在评估肿瘤组织检测在为转移性或局部晚期结直肠癌患者选择治疗方案中的应用效果。