Crnic Institute Human Trisome Project - Trisomy 21 Model Atlas: PolyA RNA-seq from 9-month old mouse brain cortex tissue

Analysis of steady-state mRNA levels in mouse brain cortex tissue at 9 months from wild-type C57BL/6J, Dp16, 5xFAD, and 5xFAD-Dp16 mice. Overall design: Comparison of wild-type (n=4), Dp16 (n=4), 5xFAD (n=4), and 5xFAD-Dp16 (n=4) mice.

本研究对9月龄野生型C57BL/6J、Dp16、5xFAD及5xFAD-Dp16小鼠的大脑皮层组织进行稳态mRNA水平分析。实验总体设计：对野生型（n=4）、Dp16（n=4）、5xFAD（n=4）以及5xFAD-Dp16（n=4）小鼠开展对照比较分析。