Additional file 2 of Cortistatin deficiency reveals a dysfunctional brain endothelium with impaired gene pathways, exacerbated immune activation, and disrupted barrier integrity

Additional file 2: Table S3. Differentially expressed genes (DEGs) in Cort−/−  BECs in NX/NG compared to Cort+/+ BECs. Table S4. Differentially expressed genes (DEGs) in Cort−/− BECs in OGD-R compared to Cort+/+ BECs. Table S5. DEGs for NX/NG-incubated Cort−/− vs Cort+/+ BECs included in Gene Ontology (GO) terms. Table S6. DEGs for OGD-R-incubated Cort−/− vs Cort+/+ BECs included in Gene Ontology (GO) terms. Table S7. Differentially expressed genes (DEGs) in the dynamics of Cort+/+ BECs from NX/NG to OGD-R. Table S8. Differentially expressed genes (DEGs) in the dynamics of Cort−/− BECs from NX/NG to OGD-R. Table S9. DEGs for Cort+/+ BECs from NX/NG to OGD-R included in Gene Ontology (GO) terms. Table S10. DEGs for Cort−/− BECs from NX/NG to OGD-R included in Gene Ontology (GO) terms. Table S11. Comparative values between log2FC and RPKM for differentially expressed genes (DEGs) depicted in Fig. 7.

补充文件2：表S3。Cort基因缺失型（Cort−/−）BECs在NX/NG培养条件下，相较于Cort野生型（Cort+/+）BECs的差异表达基因（Differentially Expressed Genes, DEGs）。表S4。Cort−/− BECs在OGD-R培养条件下，相较于Cort+/+ BECs的差异表达基因（DEGs）。表S5。经NX/NG培养的Cort−/−与Cort+/+ BECs的差异表达基因，且该类基因被纳入基因本体论（Gene Ontology, GO）术语注释集。表S6。经OGD-R培养的Cort−/−与Cort+/+ BECs的差异表达基因，且该类基因被纳入基因本体论（GO）术语注释集。表S7。Cort+/+ BECs从NX/NG培养条件向OGD-R培养条件转变的动态过程中的差异表达基因（DEGs）。表S8。Cort−/− BECs从NX/NG培养条件向OGD-R培养条件转变的动态过程中的差异表达基因（DEGs）。表S9。Cort+/+ BECs从NX/NG到OGD-R的动态变化相关差异表达基因，且该类基因被纳入GO术语注释集。表S10。Cort−/− BECs从NX/NG到OGD-R的动态变化相关差异表达基因，且该类基因被纳入GO术语注释集。表S11。图7中展示的差异表达基因的log2倍变化（log2 fold change, log2FC）与每百万映射reads每千碱基reads数（Reads Per Kilobase per Million mapped reads, RPKM）的对比数值。