Additional file 3 of A global overview of genetically interpretable multimorbidities among common diseases in the UK Biobank

Additional file 3: Supplementary Tables. Common disease summary information (Table S1). Multimorbidities among common diseases in the UK Biobank (Table S2). Multimorbidities interpreted by SNPs (Table S3). Multimorbidities interpreted by genes (Table S4). Multimorbidities interpreted by PPIs (Table S5). Multimorbidities interpreted by pathways (Table S6). Multimorbidities interpreted by genetic correlations (Table S7). Summary of universal hub diseases in the LG- and NG-networks (Table S8). Multimorbidity modules in the LG-network (Table S9). Multimorbidity modules in the NG-network (Table S10). Multimorbidity-drug-prescription relations derived from multimorbidity genes, drug targets and the UK Biobank self-report medications (Table S11). Multimorbidities among all diseases (including both common and rare diseases) in the UK Biobank (Table S12). Multimorbidity comparison with Jensen et al. [25] and Blair et al. [24] at different time windows (Table S13).

附加文件3：补充表格。常见疾病汇总信息（表S1）。英国生物样本库（UK Biobank）常见疾病间的共病情况（表S2）。基于单核苷酸多态性（SNPs）解析的共病情况（表S3）。基于基因解析的共病情况（表S4）。基于蛋白质相互作用（PPIs）解析的共病情况（表S5）。基于通路解析的共病情况（表S6）。基于遗传相关性解析的共病情况（表S7）。LG网络与NG网络中的通用枢纽疾病汇总（表S8）。LG网络中的共病模块（表S9）。NG网络中的共病模块（表S10）。基于共病基因、药物靶点及英国生物样本库（UK Biobank）自我报告用药数据推导的共病-处方药物关联（表S11）。英国生物样本库（UK Biobank）中所有疾病（含常见疾病与罕见疾病）间的共病情况（表S12）。不同时间窗下与Jensen等[25]及Blair等[24]研究的共病情况对比（表S13）。