Patient Characteristics (initial presentation)

aAge at presentation in years; dc, deceased; bHF, chronic heart failure; NYHA, classi-fication of heart failure according to the New York Heart Association; CD, cardiac death cEA, Ebstein's anomaly; dASD, atrial septal defect; eaECG, abnormal ECG; fNVM, non-compaction of the ventricular myocardium; +, affected; (+), partially affected; see Material and Methods for details on the affection status; non-isolated/isolated: with/without EA and/or ASD. Listed are all carriers of the MYH7 mutation and in addition individual III-2 who was not genotyped.a 就诊年龄（单位：岁）；dc：已去世（deceased）； b 慢性心力衰竭（chronic heart failure, HF）；NYHA：纽约心脏协会（New York Heart Association）心力衰竭分级标准；CD：心源性死亡（cardiac death） c 埃布斯坦畸形（Ebstein's anomaly, EA）； d 房间隔缺损（atrial septal defect, ASD）； ea 心电图异常（abnormal ECG, ECG）； f 心室肌致密化不全（non-compaction of the ventricular myocardium, NVM）；+：受累；(+)：部分受累；详见材料与方法部分以明确受累状态的判定细节；非孤立性/孤立性：合并/不合并EA和/或ASD。本列表收录了所有携带MYH7基因突变的携带者，此外还纳入了未进行基因分型的家系个体III-2。