Additional file 1 of Characterizing the metabolic divide: distinctive metabolites differentiating CAD-T2DM from CAD patients

Additional file 1: Figure S1. Flowchart for patient enrolment. Figure S2. Mass spectra of quality control (QC) samples. Figure S3. Density plots of the data. Figure S4. Pathway enrichment analysis of metabolites associated with T2DM (FDR<0.05). Figure S5. Distribution of characterized metabolite levels in the discovery cohort. Figure S6. Distribution of characterized metabolite levels in the validation cohort. Figure S7. BSA content after 60 h metabolite intervention. Figure S8. Heatmap of differentially expressed genes (DEGs).

附加文件1：补充图S1：患者入组流程图。补充图S2：质量控制（Quality Control, QC）样本的质谱图。补充图S3：数据集的密度分布图。补充图S4：与2型糖尿病（Type 2 Diabetes Mellitus, T2DM）相关代谢物的通路富集分析（错误发现率<0.05，FDR<0.05）。补充图S5：发现队列中已注释代谢物水平的分布情况。补充图S6：验证队列中已注释代谢物水平的分布情况。补充图S7：代谢物干预60小时后的牛血清白蛋白（Bovine Serum Albumin, BSA）含量。补充图S8：差异表达基因（Differentially Expressed Genes, DEGs）的热图。