File S1 - Kinetic Partitioning Modulates Human Telomere DNA G-Quadruplex Structural Polymorphism
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Supporting figures. Figure S1, Gaussian fitting of smFRET distribution of Tel23 molecules thermally annealed and imaged in 20 mM KCl. Figure S2, in situ unfolding of thermally annealed Tel23 molecules. Figure S3, Single-molecule FRET histograms of Tel23 in situ refolded in 60mM and 20mM KCl for the indicated period of time. Figure S4, Gaussian fitting of Tel23 and Tel22 smFRET distributions. Figure S5, Atomic resolution structures of the parallel, anti-parallel, and a hybrid telomere DNA GQ conformations. (DOCX)
辅助图表。图S1：经热退火处理并在20 mM氯化钾溶液中成像的Tel23分子的单分子荧光共振能量转移（smFRET）分布的高斯拟合结果；图S2：热退火后的Tel23分子的原位解折叠过程；图S3：Tel23分子在60 mM与20 mM氯化钾溶液中按指定时长原位复性后的单分子荧光共振能量转移直方图；图S4：Tel23与Tel22的smFRET分布的高斯拟合结果；图S5：平行、反平行及混合型端粒DNA G-四链体（G-quadruplex，GQ）构象的原子分辨率结构。（文件格式为DOCX）
