Surgical treatment for thyroid carcinoma: retrospective study with 811 patients in a Brazilian tertiary hospital

ABSTRACT Objective The aim of the present study was to describe the epidemiologic data, histological type, treatment and follow-up of the 811 patients treated for thyroid cancer in Instituto do Câncer do Estado de São Paulo (ICESP) over 5 years. Materials and methods Retrospective analyses of electronic chart information. Results There were 679 cases (83.7%) of papillary thyroid cancer, 61 (7.5%) of follicular carcinoma, 54 (6.7%) of medullary carcinoma, 11 (1.4%) of poorly differentiated carcinoma and 6 of anaplastic carcinoma (0.7%). The majority of patients were female (82.2%), and the mean age was 50.5 ± 15 years. Two hundred forty-two patients had disease persistence or recurrence. At the last follow-up, 629 (77.6%) patients were alive and disease free, 141 (17.4%) were alive with disease, and 41 (5.1%) were deceased, with 37 deaths related to thyroid cancer. Conclusion This study was able to outline the profile, disease type and evolution of patients treated for thyroid cancer at a single tertiary hospital.

摘要
研究目的：本研究旨在描述圣保罗州癌症研究所（Instituto do Câncer do Estado de São Paulo, ICESP）5年间收治的811例甲状腺癌患者的流行病学资料、组织学类型、治疗方案及随访情况。
材料与方法：对电子病历资料开展回顾性分析。
结果：本研究纳入的患者中，乳头状甲状腺癌（papillary thyroid cancer）679例（占83.7%）、滤泡状癌（follicular carcinoma）61例（7.5%）、髓样癌（medullary carcinoma）54例（6.7%）、低分化癌（poorly differentiated carcinoma）11例（1.4%）、未分化癌（anaplastic carcinoma）6例（0.7%）。患者以女性居多，占比82.2%，平均年龄为50.5±15岁。共计242例患者出现病灶残留或疾病复发。末次随访时，629例（77.6%）患者无病生存，141例（17.4%）带瘤生存，41例（5.1%）死亡，其中37例死因与甲状腺癌相关。
结论：本研究阐明了单中心三级医院收治的甲状腺癌患者的人群特征、疾病类型及转归规律。