Crystal structure of KDM2A histone demethylase catalytic domain in complex with an H3C36 peptide modified by UNC8015

Crystal structure of KDM2A histone demethylase catalytic domain in complex with an H3C36 peptide modified by UNC8015 Descriptor: FE (III) ION, Histone H3.2, Lysine-specific demethylase 2A, ... Authors: Budziszewski, G.R, Azzam, D.N, Spangler, C.J, Skrajna, A, Foley, C.A, James, L.I, Frye, S.V, McGinty, R.K. Deposit date: 2022-04-29 Release date: 2023-02-22 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural basis of paralog-specific KDM2A/B nucleosome recognition. Nat.Chem.Biol., 19, 2023

KDM2A组蛋白去甲基化酶催化结构域与经UNC8015修饰的H3C36肽段形成复合物的晶体结构。描述项：三价铁离子（Fe(III)）、组蛋白H3.2、赖氨酸特异性去甲基化酶2A等。作者：Budziszewski, G.R、Azzam, D.N、Spangler, C.J、Skrajna, A、Foley, C.A、James, L.I、Frye, S.V、McGinty, R.K。提交日期：2022-04-29；发布日期：2023-02-22；最后修订日期：2024-10-16。实验方法：X射线衍射（分辨率1.98埃）。引用文献：《旁系同源特异性KDM2A/B核小体识别的结构基础》，《自然-化学生物学》，第19卷，2023年。