Table_2_A Gene Expression Atlas of the Domestic Water Buffalo (Bubalus bubalis).xlsx

The domestic water buffalo (Bubalus bubalis) makes a major contribution to the global agricultural economy in the form of milk, meat, hides, and draught power. The global water buffalo population is predominantly found in Asia, and per head of population more people depend upon the buffalo than on any other livestock species. Despite its agricultural importance, there are comparatively fewer genomic and transcriptomic resources available for buffalo than for other livestock species. We have generated a large-scale gene expression atlas covering multiple tissue and cell types from all major organ systems collected from three breeds of riverine water buffalo (Mediterranean, Pandharpuri and Bhadawari) and used the network analysis tool Graphia Professional to identify clusters of genes with similar expression profiles. Alongside similar data, we and others have generated for ruminants as part of the Functional Annotation of Animal Genomes Consortium; this comprehensive transcriptome supports functional annotation and comparative analysis of the water buffalo genome.

家养水牛（Bubalus bubalis）以乳、肉、皮及役用能力为载体，为全球农业经济作出了重要贡献。全球水牛种群主要分布于亚洲，且相较于其他任何畜牧物种，依赖水牛的人口规模更为可观。尽管水牛在农业领域具有核心地位，但相较于其他畜牧物种，可供研究的水牛基因组与转录组资源相对匮乏。我们采集了三个河流型水牛品种（地中海水牛、潘德哈里水牛（Pandharpuri）与巴达瓦里水牛（Bhadawari））所有主要器官系统的多种组织与细胞类型样本，构建了大规模基因表达图谱，并借助网络分析工具Graphia Professional识别出表达谱相似的基因簇。作为动物基因组功能注释联盟（Functional Annotation of Animal Genomes Consortium）的成员，我们与其他研究者同步生成了反刍动物的同类数据集；这套完整的转录组数据可为水牛基因组的功能注释与比较分析提供坚实支撑。