BindingDB Entry 50018558: Targeting Gatekeeper Mutations for Kinase Drug Discovery.

Small molecule binding data for protein ALK tyrosine kinase receptor, Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 4, Macrophage colony-stimulating factor 1 receptor, Mast/stem cell growth factor receptor Kit, Platelet-derived growth factor receptor alpha, Platelet-derived growth factor receptor alpha/beta, Proto-oncogene tyrosine-protein kinase receptor Ret, and Receptor-type tyrosine-protein kinase FLT3, Uniprot P05622, P07333, P07949, P10721, P11362, P16234, P21802, P22455, P22607, P26618, P36888, Q03142, and Q9UM73

本数据集涵盖以下蛋白的小分子结合数据：ALK酪氨酸激酶受体（ALK tyrosine kinase receptor）、成纤维细胞生长因子受体1（Fibroblast growth factor receptor 1）、成纤维细胞生长因子受体2（Fibroblast growth factor receptor 2）、成纤维细胞生长因子受体3（Fibroblast growth factor receptor 3）、成纤维细胞生长因子受体4（Fibroblast growth factor receptor 4）、巨噬细胞集落刺激因子1受体（Macrophage colony-stimulating factor 1 receptor）、肥大细胞/干细胞生长因子受体Kit（Mast/stem cell growth factor receptor Kit）、血小板衍生生长因子受体α（Platelet-derived growth factor receptor alpha）、血小板衍生生长因子受体α/β（Platelet-derived growth factor receptor alpha/beta）、原癌基因酪氨酸蛋白激酶受体Ret（Proto-oncogene tyrosine-protein kinase receptor Ret）以及受体型酪氨酸激酶FLT3（Receptor-type tyrosine-protein kinase FLT3），对应UniProt数据库条目号为P05622、P07333、P07949、P10721、P11362、P16234、P21802、P22455、P22607、P26618、P36888、Q03142及Q9UM73。