National Survey of Sexual Attitudes and Lifestyles, 2010-2012: Biological Data: Secure Access

The <i>British National Surveys of Sexual Attitudes and Lifestyles</i>, or Natsal, are among the largest and most detailed studies of sexual behaviour in the world. Three Natsal surveys have taken place to date: Natsal-1 in 1990-1991 (available from the UK Data Archive under SN 3434), Natsal-2 in 1999-2001 (available under SN 5223) and Natsal-3 in 2010-2012 (available under SN 7799, and for Secure Access versions SN 8178 and SN 8179). Further information is available from the <a class="external" href="http://www.natsal.ac.uk/home.aspx" title="Natsal">Natsal</a> website.<br>
The <i>National Survey of Sexual Attitudes and Lifestyles, 2010-2012</i> is the third survey in the series. Natsal-3 aimed to provide up-to-date information on key sexual behaviours and risk factors, as well as to look at trends over time by including comparable measures to those used in the previous two surveys, and to include new questions and an extended age range to take account of current information needs in the field of sexual health. <br>
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The main objectives of Natsal-3 were to: <ul><li>provide a detailed understanding of patterns and variability of sexual behaviour in Britain (including, for example, numbers of sexual partners, frequency of different sexual practices, and homosexual experience) </li><li>provide self-reported estimates of a range of sexual and reproductive health outcomes (including, for example, pregnancy, STI diagnosis, contraception use) and health service use</li><li>explore sexual behaviour and function over the life-course by including an older age group (up to age 74) </li><li>describe changes in sexual activity over time and trends in relationships, reproductive history and patterns of fertility (using Natsal-1, Natsal-2 and Natsal-3) </li><li>from urine samples, measure the prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, type-specific Human Papillomavirus, HIV antibody and Mycoplasma genitalium</li><li>measure the gender-specific distribution of salivary testosterone and its relationship to sexual behaviour, function and ageing</li></ul><b>Secure Access Datasets</b><br>
The Natsal-3 Secure Access datasets include additional variables considered too sensitive or disclosive for release under standard End User Licence (EUL) conditions. Additional variables available in the Secure Access studies (SNs 8178 and 8179) include:<ul><li>detailed geographic variables, including Local Authority Districts and Area Classification for Output Areas Subgroups</li><li>respondent month of birth</li><li>age when had hysterectomy</li><li>month and year of first and most recent sex with partners</li><li>outcomes of pregnancies</li><li>age at first stillbirth</li><li>variables relating to abortions</li><li>age at miscarriage, abortion or still birth</li><li>month of last pregnancy</li><li>genders and month of birth of children</li><li>number of children gave birth to in multiple births</li><li>ungrouped ethnic group</li><li>age when first and last injected non-prescribed drugs</li><li>dates (months) relating to live-in partners</li><li>qualifications</li><li>Indices of Multiple Deprivation</li></ul>This study, SN 8179 (National Survey of Sexual Attitudes and Lifestyles, 2010-2012: Biological Data: Secure Access), includes all the variables listed above, plus variables relating to urine and saliva sample tests, including:<ul><li>chlamydia</li><li>gonorrhoea</li><li>Mycoplasma genitalium</li><li>HIV</li><li>HPV</li><li>Trichomonas vaginalis</li><li>salivary testosterone level</li></ul>

《英国全国性态度与生活方式调查》（*British National Surveys of Sexual Attitudes and Lifestyles*，简称Natsal）是全球范围内规模最大、内容最详实的性行为研究项目之一。截至目前，该系列已开展三轮调研：1990-1991年的Natsal-1（可从英国数据档案馆（UK Data Archive）获取，编号SN 3434）、1999-2001年的Natsal-2（编号SN 5223），以及2010-2012年的Natsal-3（编号SN 7799；安全访问版编号为SN 8178与SN 8179）。更多信息可登录Natsal官方网站（http://www.natsal.ac.uk/home.aspx）查询。

《2010-2012年全国性态度与生活方式调查》是该系列的第三轮调研。Natsal-3旨在提供关键性行为与风险因素的最新数据，同时通过沿用前两轮调研的可比测量指标追踪长期趋势，并新增调研问题与拓展年龄范围，以适应当前性健康领域的信息需求。

Natsal-3的核心研究目标包括：
- 全面解析英国人群性行为的模式与个体差异，涵盖性伴侣数量、不同性行为实践的发生频率、同性性行为经历等维度；
- 基于自我报告，获取一系列性与生殖健康结局（包括妊娠、性传播感染诊断、避孕措施使用情况）及医疗服务利用情况的估算数据；
- 通过纳入74岁及以上的老年群体，探究人生不同阶段的性行为与性功能变化；
- 结合Natsal-1、Natsal-2与Natsal-3的调研数据，描述性行为随时间的变迁趋势，以及伴侣关系、生殖史与生育模式的演变；
- 通过尿液样本检测，测算沙眼衣原体（*Chlamydia trachomatis*）、淋病奈瑟菌（*Neisseria gonorrhoeae*）、分型人乳头瘤病毒（*Human Papillomavirus*，HPV）、HIV抗体以及生殖支原体（*Mycoplasma genitalium*）的感染率；
- 分析唾液睾酮水平的性别分布特征，及其与性行为、性功能和衰老的关联。

**安全访问数据集**
Natsal-3的安全访问数据集包含了因敏感性较高或可能泄露隐私，无法通过标准最终用户许可协议（*End User Licence*，EUL）公开的额外变量。安全访问版本（SN 8178与SN 8179）新增的变量包括：
- 精细化地理变量，如地方政府辖区、产出区亚组区域分类；
- 受访者出生月份；
- 子宫切除术时的年龄；
- 首次与最近一次性行为发生的月份与年份；
- 妊娠结局；
- 首次死产时的年龄；
- 与流产相关的变量；
- 流产、引产或死产时的年龄；
- 末次妊娠的月份；
- 子女的性别与出生月份；
- 多胎妊娠的分娩子女数量；
- 未分组的种族群体信息；
- 首次与末次注射非处方药物时的年龄；
- 与同居伴侣相关的日期（月份）；
- 学历背景；
- 多重贫困指数（*Indices of Multiple Deprivation*）。

本研究SN 8179（《2010-2012年全国性态度与生活方式调查：生物样本数据：安全访问版》）包含上述全部新增变量，同时涵盖与尿液、唾液样本检测相关的变量，具体包括：
- 沙眼衣原体检测；
- 淋病奈瑟菌检测；
- 生殖支原体检测；
- HIV检测；
- 人乳头瘤病毒检测；
- 阴道毛滴虫（*Trichomonas vaginalis*）检测；
- 唾液睾酮水平测定。