Best practices for differential accessibility analysis in single-cell epigenomics

This submission is a dataset of single-nucleus multi-omics of uninjured and injured spinal cords of mice harvested and profiled using 10x Multiome ATAC + Gene Expression kit. Overall design: We used single-nucleus RNA-sequencing and single-nucleus ATAC-sequencing to profile the mid thoracic spinal cord of uninjured and injured mice at acute and chronic post-spinal cord injury.

本提交数据集为采用10x Multiome ATAC+基因表达试剂盒（10x Multiome ATAC + Gene Expression kit）采集并分析的小鼠未损伤与损伤脊髓的单细胞核多组学数据集。实验设计概述：本研究通过单细胞核RNA测序与单细胞核ATAC测序，对脊髓损伤后急性期与慢性期的未损伤及损伤小鼠的胸段中段脊髓开展了测序分析。