Electrocardiogram (EKG) measurements in mice treated with bufalin and 3-phospho-bufalin.
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Electrocardiogram (EKG) measurements in ICR mice treated with different doses of bufalin and 3-phospho-bufalin. EKG was measured 5 min before drug administration and 5, 10, 15 min and 24 h after drug administration. Significant changes in EKG output were highlighted in italics. While bufalin at high does induces acute cardiotoxicity, 3-phospho-bufalin is well tolerated up to 11.25 mg/kg. The measurements were performed in 3 mice. EKG parameters are presented as mean±SD.Electrocardiogram (EKG) measurements in mice treated with bufalin and 3-phospho-bufalin.
创建时间：
2015-12-03
