Electrocardiogram (EKG) measurements in mice treated with bufalin and 3-phospho-bufalin.

Electrocardiogram (EKG) measurements in ICR mice treated with different doses of bufalin and 3-phospho-bufalin. EKG was measured 5 min before drug administration and 5, 10, 15 min and 24 h after drug administration. Significant changes in EKG output were highlighted in italics. While bufalin at high does induces acute cardiotoxicity, 3-phospho-bufalin is well tolerated up to 11.25 mg/kg. The measurements were performed in 3 mice. EKG parameters are presented as mean±SD.Electrocardiogram (EKG) measurements in mice treated with bufalin and 3-phospho-bufalin.本数据集收录了经不同剂量蟾毒灵（bufalin）与3-磷酸蟾毒灵（3-phospho-bufalin）处理的ICR小鼠的心电图（EKG）检测数据。检测分别于给药前5分钟、给药后5、10、15分钟及24小时进行。心电图输出结果中的显著变化以斜体标注。高剂量蟾毒灵可诱发急性心脏毒性，而3-磷酸蟾毒灵在11.25 mg/kg剂量下仍具有良好耐受性。本次检测共使用3只小鼠完成。心电图参数以平均值±标准差（mean±SD）的形式呈现。本数据集涵盖经蟾毒灵与3-磷酸蟾毒灵处理的小鼠的心电图检测数据。