Raw Data - Effects of Different Concentration of Reversine to Enhance Conversion of Dedifferentiated Fat Cells into Cardiomyocyte

ANOVA with Tukey post-hoc analysis revealed that Reversine 10 blob:https://figshare.com/ba4755c4-9150-44f8-90dd-accfd72565a4M had greater Flk-1 expression compared to the control group (MD: 5.037+0.998; p<0.001), but there are no significant changes among Oct4 (MD: 0.013+1.244; p=0.99) and Brachyuri expression (MD: 0.157+0.084; p=0.252). Kruskal-Wallis revealed that expression of GATA4 (1.65[0.41-1.98] to 0.015[0.007-0.034]; p=0.017) reduced significantly and cTnT (5.07[6.62-8.91] to 8.22[6.81-9.40]; p=0.001) increased significantly at day-21.

采用方差分析（ANOVA）结合图基事后检验（Tukey post-hoc analysis），结果显示：与对照组相比，10 μM瑞维吉宁（Reversine）处理组的胎肝激酶1（FLK-1）表达水平显著更高（均数差[MD]：5.037±0.998；p<0.001）；而八聚体结合转录因子4（Oct4）（均数差[MD]：0.013±1.244；p=0.99）与短尾转录因子（Brachyury）的表达水平（均数差[MD]：0.157±0.084；p=0.252）均无显著变化。克鲁斯卡尔-沃利斯检验（Kruskal-Wallis test）结果表明，在第21天时，GATA结合蛋白4（GATA4）的表达水平从1.65[0.41-1.98]显著降至0.015[0.007-0.034]（p=0.017），心肌肌钙蛋白T（cTnT）的表达水平则从5.07[6.62-8.91]显著升至8.22[6.81-9.40]（p=0.001）。