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Cell atlas of the regenerating human liver after portal vein embolization

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NIAID Data Ecosystem2026-03-12 收录
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https://data.mendeley.com/datasets/yp3txzw64c
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资源简介:
Processed single-cell and single-nucleus RNA-seq data for "Cell atlas of the regenerating human liver after portal vein embolization". Original in https://www.biorxiv.org/content/10.1101/2021.06.03.444016v1. Data is deposited as RDS files, RData, and a csv file. The RDS/RData contain Seurat v3 objects. Full list of author contributions can be found in the associated manuscript. Brief description of data files: - allcells_css_annot.rds - Seurat containing all cells (scRNA-seq), along with various annotations (see figs 2 and 5 in the associated manuscript). - hep_zonation_metadata.csv - Table in csv format containing inferred zonation values for hepatocytes. Can be combined with hepatocytes from the previous file. - endothelial_cells_annot.rds - Seurat containing only the endothelial cells, and including more annotation of those populations (see fig 4 in the associated manuscript). - frozen_tissue_dataset.rdata - Seurat containing all nuclei (snRNA-seq) and corresponding annotations (see fig 1 of the associated manuscript)

本数据集对应研究《门静脉栓塞术后再生人肝脏细胞图谱》(Cell atlas of the regenerating human liver after portal vein embolization),包含经过预处理的单细胞RNA测序(single-cell RNA-seq, scRNA-seq)与单细胞核RNA测序(single-nucleus RNA-seq, snRNA-seq)数据。相关原始研究见于:https://www.biorxiv.org/content/10.1101/2021.06.03.444016v1。 数据集以RDS文件、RData文件及CSV文件形式存档,其中RDS/RData文件内含Seurat v3分析对象。 完整的作者贡献说明可参阅该关联预印本手稿。 数据文件简要说明如下: - allcells_css_annot.rds:包含全部细胞的Seurat对象(对应scRNA-seq数据),附带多种注释信息(详见关联论文的图2与图5)。 - hep_zonation_metadata.csv:CSV格式表格,包含推断得到的肝细胞分区值,可与前述文件中的肝细胞数据合并使用。 - endothelial_cells_annot.rds:仅包含内皮细胞的Seurat对象,附带该类细胞群的更详细注释信息(详见关联论文的图4)。 - frozen_tissue_dataset.rdata:包含全部细胞核的Seurat对象(对应snRNA-seq数据)及其对应注释信息(详见关联论文的图1)。
创建时间:
2021-08-09
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